The joint project MyPathSem deals with the widespread disease of cancer. In the treatment of cancer, it is increasingly necessary to expand the focus from individual molecular biomarkers to entire signaling networks. This approach is made possible by the latest omics technologies, which allow the simultaneous measurement of thousands of markers. However, the challenge now lies in reducing the resulting flood of measurement data to a sensible level and then making it available to the scientist or doctor in routine treatment in a clear manner.

This is where the joint project MyPathSem comes in: The aim of the project is to establish a new type of infrastructure for the treatment of colorectal cancer. To this end, a comprehensive signaling network database is being developed based on the commercially distributed platform of the industrial partner involved in the joint project. This database will contain both patient-related omics data and extensive knowledge from the relevant scientific literature. As soon as the database exists, methods will be sought that condense the knowledge from this database. In this way, the signaling networks relevant for the treatment of cancer patients will be identified. Finally, an information presentation system is to be established which, on the basis of this information, will help the clinical researcher or treating physician to select the best possible treatment.