In diesem Sommersemester wird die im WiSe 2022/23 erfolgreich gestartete Vortragsreihe Medical Information Sciences fortgesetzt. Renommierte Wissenschaftlerinnen und Wissenschaftler unterschiedlicher Fachdisziplinen und Forschungsstandorte geben jeden Dienstag ab 17:30 Uhr Einblicke in aktuelle Fragestellungen und Anwendungsgebiete des breiten Forschungsfeldes Medical Information Sciences.

Computational models and analyses play a crucial role in drug research and development across various stages. These models have become an integral part of the drug development process, addressing a range of challenges. There are two main types of approaches used in these applications: 1) Mechanistic models are utilized to address smaller scale biology and engineering related questions. They help optimize drug design, target engagement, dosing, and PK/PD (pharmacokinetics/pharmacodynamics). 2) Machine learning and statistical models are employed for larger-scale OMICS data analysis. They aid in identifying and characterizing targets, selecting patient populations, and understanding biomarkers of response or resistance. This presentation will showcase recent examples in both areas and explore potential future opportunities for Systems Biology modeling in drug research and development.